Creating Hybrid Genes by Homologous Recombination
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چکیده
منابع مشابه
Creating Hybrid Genes by Homologous Recombination
Recombination of homologous genes is a powerful mechanism for generating sequence diversity, and can be applied to protein analysis and directed evolution. In vitro recombination methods such as DNA shuffling are very flexible and can give hybrid genes with multiple crossovers; they have been used extensively to evolve proteins with improved and novel properties. In vivo recombination in both E...
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DNA damage, in the form of DNA double-strand breaks, poses a considerable threat to genomic integrity and cell survival. If left unrepaired, a single double-strand break is sufficient to cause cell death and, if repaired inappropriately, a double-strand break may give rise to a potentially oncogenic translocation. Double-strand breaks in genomic DNA may arise accidentally in a number of ways, i...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2000
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2000/596468